Metabolomic Medicine^® Research  
 

1. Developing BIOTEL: A Semi-Automated Spreadsheet for Estimating Telomere Length and Biological Age. 
   
   Tsatsakis Aristidis, Tsoukalas Dimitrios, Fragkiadaki Persefoni, Vakonaki Elena, Tzatzarakis Manolis, Sarandi Evangelia, Nikitovic Dragana, Tsilimidos Gerasimos, Alegakis Athanasio.
   
   Frontiers in Genetics 2019-02-19 | journal-article DOI: https://doi.org/10.3389/fgene.2019.00084  
    
2. A Polyphenol-Enriched Supplement Exerts Potent Epigenetic-Protective Activity in a Cell-Based Model of Brain Ischemia. 
   
   Lara Faggi 1,†, Vanessa Porrini 1,†, Annamaria Lanzillotta 1, Marina Benarese 1, Mariana Mota 1, Dimitris Tsoukalas 2, Edoardo Parrella 1, and Marina Pizzi 1.
    
   1. Department of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy
   2. European Institute of Nutritional Medicine, E.I.Nu.M., Viale Liegi 44, 00198 Rome, Italy
   
   Nutrients 2019, 11(2), 345; https://doi.org/10.3390/nu11020345 
    
3. Gut microbiome metagenomics to understand how xenobiotics impact human health. 
   
   Robin Mesnage and Michael N. Antoniou and Dimitrios Tsoukalas and George N. Goulielmos and Aristides M. Tsatsakis.
   
   Current Opinion in Toxicology 2019-02 | journal-article DOI: 10.1016/j.cotox.2019.02.002 
    
4. Effect of chronic and heavy drug abuse on biological aging.   
   
   Vakonaki, E., Tzatzarakis, M., Tsiminikaki, K., Nathena, D., Fragkiadaki, P., Kalliantasi, K., Kanaki, K., Vaki, G., Plaitis, S., Tsoukalas, D., Alegakis, A., Spandidos, D. A., Tsatsakis, A.
   
   World Academy of Sciences Journal 2019-02-05 | journal-article DOI: 10.3892/wasj.2019.7
    
5. Application of metabolomics part II: Focus on fatty acids and their metabolites in healthy adults
   Authors: Dimitrios Tsoukalas, Athanasios K. Alegakis, Persefoni Fragkiadaki, Evangelos Papakonstantinou, Gerasimos Tsilimidos, Franco Geraci, Evangelia Sarandi, Dragana Nikitovic, Demetrios A. Spandidos, Aristides Tsatsakis.
   
   Affiliations: Laboratory of Toxicology and Forensic Sciences, Medical School, University of Crete, 71003 Heraklion, Greece, Metabolomic Medicine Clinic, 10674 Athens, Greece, European Institute of Nutritional Medicine, E.I.Nu.M, 00198 Rome, Italy, Laboratory of Anatomy‑Histology-Embryology, School of Medicine, University of Crete, 71003 Heraklion, Greece, Laboratory of Clinical Virology, School of Medicine, University of Crete, 71003 Heraklion, Greece
   
   International Journal of Molecular Medicine. Published online on: November 14, 2018 https://doi.org/10.3892/ijmm.2018.3989
   Copyright: © Tsoukalas et al. This is an open-access article distributed under the terms of Creative Commons Attribution License.
    
6. Efficacy of a Mediterranean diet supplemented with fatty fish in ameliorating inflammation in paediatric asthma: a randomised controlled trial. 
   
   M. M. Papamichael,¹ Ch. Katsardis,² K. Lambert,³ D. Tsoukalas,⁴ M. Koutsilieris^,2 B. Erbas³ & C. Itsiopoulos¹
   1. Department of Rehabilitation, Nutrition & Sport, School of Allied Health, La Trobe University, Melbourne, VIC, Australia. 
   2. National & Kapodistrian University of Athens, Athens, Greece
   3. Department of Public Health, School of Psychology & Public Health, La Trobe University, Melbourne, VIC, Australia
   4. European Institute of Nutritional Medicine, Rome, Italy
   
   J Hum Nutr Diet. 2018 Oct 30. doi: 10.1111/jhn.12609. The official journal of the British Dietetic Association. 
    
7. The Akt pathway in oncology therapy and beyond (Review). 
   Nitulescu GM, Van De Venter M, Nitulescu G, Ungurianu A, Juzenas P, Peng Q, Olaru OT, Grădinaru D, Tsatsakis A, Tsoukalas D, Spandidos DA, Margina D.
   
   1. Faculty of Pharmacy, 'Carol Davila' University of Medicine and Pharmacy, 020956 Bucharest, Romania.
   2. Department of Biochemistry and Microbiology, Nelson Mandela University, Port Elizabeth 6031, South Africa.
   3. Department of Pathology, Radiumhospitalet, Oslo University Hospital, 0379 Oslo, Norway.
   4. Department of Forensic Sciences and Toxicology, Faculty of Medicine, University of Crete, 71003 Heraklion, Greece.
   5. Laboratory of Clinical Virology, School of Medicine, University of Crete, 71003 Heraklion, Greece.
   
   Int J Oncol. 2018 Oct 16. doi: 10.3892/ijo.2018.4597
    
8. Decreased telomeres length in patients with glioblastoma multiform 
   E.K.Vakonaki, G.A.Vaki, K.Tsiminikaki, A.Alegkakis K.Kalliantasi, P. Fragkiadaki, M.Flamourakis,
   D. Tsoukalas, I. Fragkiadoulaki, M.N.Tzatzarakis, A.M.Tsatsakis
   
   Medical School, University of Crete, Laboratory of Toxicology, Heraklion, Crete, Greece
   
   Toxicology Letters Volume 295, Supplement 1, 10 October 2018, Page S92
   https://doi.org/10.1016/j.toxlet.2018.06.582 
    
9. Urinary organic acids as biomarkers in the assessment of pulmonary function in children with asthma
   Maria Michelle Papamichael^a, Chris Katsardis^c, Bircan Erbas^b, Catherine Itsiopoulos^a, Dimitris Tsoukalas<sup>d
   
   a</sup> La Trobe University, School of Allied Health, Department of Rehabilitation, Nutrition & Sport, Melbourne, Australia
   ^b La Trobe University, School of Psychology & Public Health, Department of Public Health, Melbourne, Australia
   ^c National & Kapodistrian University of Athens, Athens, Greece
   ^d European Institute of Nutritional Medicine, Rome, Italy
   
   Nutrition Research, Elsevier. October 2018. https://doi.org/10.1016/j.nutres.2018.10.004 
    
10. World aging population, chronic diseases and impact of modifiable-metabolic risk factors
    
    Dr. Dimitris Tsoukalas, MD (Greece). European Institute of Nutritional Medicine, E.I.Nu.M.
    
    20th International Congress of Rural Medicine 2018. Tokyo - Japan. 
     
11. Merging precision medicine and biology of aging in aging-related diseases
    
    Tsoukalas D. Physician. European Institute of Nutritional Medicine, E.I.Nu.M.
    
    Healthy Ageing an endless challenge. 35th Balkan Medical Week Congress, 25-17 Sept. 2018 Athens Greece
     
12. The effect of supplements on telomere length
    
    Fragkiadaki P^1,2, Tsoukalas D^1,3, Alegkakis A1, Sarandi E^1,3, Tsatsakis A^1,2
    
    1.Center of Toxicology Science and Research, University of Crete, Heraklion, Crete, Greece
    2. Toxplus spin off S.A., Heraklion 71601
    3. Metabolomic Medicine Clinic, Athens 10674
    
    Healthy Ageing an endless challenge. 35th Balkan Medical Week Congress, 25-17 Sept. 2018 Athens Greece
     
13. Modulation of the Process of Aging in Human Organism: Recent Advances in Biomarkers for Diagnosis and Treatment 
    
    Tsoukalas, Dimitrios; Fragkiadaki, Persefoni; Sarandi, Evangelia; Tsatsakis, Aristidis.
    
    2018 11(2): 146-156; Journal of Siberian Federal University SibFU Journals Biology 
     
14. Stanozolol administration combined with exercise leads to decreased telomerase activity possibly associated with liver aging. 
    
    Authors: Eren Ozcagli Mehtap Kara Tugba Kotil Persefoni Fragkiadaki Manolis N. Tzatzarakis Christina Tsitsimpikou Polychronis D. Stivaktakis Dimitrios Tsoukalas Demetrios A. Spandidos Aristides M. Tsatsakis Buket Alpertunga.
    
    April 2018. International Journal of Molecular Medicine. DOI10.3892/ijmm.2018.3644 
     
15. Fatty fish (Ù3) – A diet therapy for paediatric asthma?
    
    Papamichael Maria Michelle, Êatsardis Charis, Koutsilieris Michael, Tsoukalas Dimitris, Lambert Katrina, Erbas Bircan, Itsiopoulos Catherine.  
    
    World Congress on Nutrition and Dietetics, June 18-19, Paris, France. J Clin Nutr Diet 2018 Volume: 4. DOI: 10.4172/2472-1921-C1-002.
     
16. The prophylactic potential of fatty fish consumption on airway inflammation in childhood asthma. 
    
    Papamichael Maria Michelle, Êatsardis Charis, Koutsilieris Michael, Tsoukalas Dimitris, Lambert Katrina, Erbas Bircan, Itsiopoulos Catherine.
    
    17th American Pediatrics Healthcare & Infectious Diseases Congress June 27-28 2018, Vancouver, Canada.
     
17. Omega 3 fatty acids- A new therapeutic target for childhood asthma? 
    
    Papamichael Maria Michelle, Êatsardis Charis, Koutsilieris Michael, Tsoukalas Dimitris, Lambert Katrina, Erbas Bircan, Itsiopoulos Catherine.
    
    14th International Congress on Advances in Natural Medicines, Nutraceuticals & Neurocognition, July 19-20, 2018 London, UK.
     
18. Application of metabolomics: Focus on the quantification of organic acids in healthy adults. 
    
    Tsoukalas D 1-2, Alegakis A1, Fragkiadaki P1, Papakonstantinou E2, Nikitovic D3, Karataraki A2, Nosyrev AE4, Papadakis EG5, Spandidos DA6, Drakoulis N7, Tsatsakis AM1.
    
    1. Laboratory of Forensic Sciences and Toxicology, Medical School, University of Crete, Heraklion 71003, Greece.
    2. Metabolomic Medicine Clinic, Athens 10674, Greece.
    3. Laboratory of Anatomy‑Histology‑Embryology, School of Medicine, University of Crete, Heraklion 71003, Greece.
    4. I.M. Sechenov First Moscow State Medical University, Moscow 119048, Russia.
    5. Onassis Cardiac Surgery Centre, Athens 17674, Greece.
    6. Laboratory of Clinical Virology, School of Medicine, University of Crete, Heraklion 71003, Greece.
    7. Research Group of Clinical Pharmacology and Pharmacogenomics, Faculty of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Athens 15772, Greece.
    
    Int J Mol Med. 2017 May 10. doi: 10.3892/ijmm.2017.2983.
     
19. A clinical trial on the efficacy of a Mediterranean diet enriched with fatty fish in the management of paediatric asthma: Preliminary results. 
    
    Papamichael M, Katsardis C, Tsoukalas D, Erbas B, Itsiopoulos C. Clin Nutr ESPEN. 2018 Apr;24:184. doi: 10.1016/j.clnesp.2018.01.047. Epub 2018 Mar 22
    
    1. La Trobe University, School of Allied Health, Australia.
    2. National & Kapodistrian University of Athens, Athens, Greece.
    3. European Institute of Nutritional Medicine, Rome.
    4. La Trobe University, School of Public Health, Australia.

20. Common mental disorders and association with telomere length (Review). 

    Authors: E. Vakonaki, K. Tsiminikaki, S. Plaitis, P. Fragkiadaki, D. Tsoukalas, I. Katsikantami, G. Vaki, M. N. Tzatzarakis, D. A. Spandidos, A. M. Tsatsakis.
    Affiliations: Laboratory of Toxicology Science and Research, Medical School, University of Crete, 71003 Heraklion, Crete, Greece, Laboratory of Clinical Virology, Medical School, University of Crete, 71409 Heraklion, Crete, Greece. Biomedical Reports 2018-01-08 | journal-article DOI: 10.3892/br.2018.1040 Part of ISSN: 2049-9434

     

21. Do flavanols-rich natural products relieve obesity-related insulin resistance? 
    Tsatsakis b, Dimitris Tsoukalas c, Atilla Engin d 
    a. Gazi University, Faculty of Pharmacy, Department of Toxicology, Hipodrom, Ankara, Turkey 
    b. Laboratory of Toxicology and Forensics, Medical School, University of Crete, Heraklion, Crete, Greece 
    c. Laboratory of Toxicology, Medical School, University of Crete, Voutes, Heraklion, Crete, Greece
    d. Gazi University, Faculty of Medicine, Department of General Surgery, Besevler, Ankara, Turkey. 
    Food and Chemical Toxicology 2017-12-27. DOI: https://doi.org/10.1016/j.fct.2017.12.055
    
    
    Description
    Highlights
    1. Obesity is recognized as chronic, low-grade inflammation and increased oxidative stress.
    2. Insulin resistance may occur due to chronic overfeeding and subsequent obesity.
    3. Dietary polyphenols may correct obesity-related insulin resistance, dose dependently.
    4. Dietary polyphenols decrease lipogenesis, increase lipolysis with the simultaneous stimulation of fatty acid oxidation.
    5. Polyphenol intake can prevent high-fat diet-induced insulin resistance via cell surface G protein-coupled estrogen receptor.

22. Current evidence on the effect of dietary polyphenols intake on chronic diseases.
    
    Chiara Costa and Aristidis Tsatsakis and Charalampos Mamoulakis and Michele Teodoro and Giusi Briguglio and Emanuela Caruso and Dimitris Tsoukalas and Denisa Margina and Efthimios Dardiotis and Demetrios Kouretas and Concettina Fenga.
    
    Food and Chemical Toxicology, Volume 110, December 2017, Pages 286-299. https://doi.org/10.1016%2Fj.fct.2017.10.023
     

23. Age-dependent endocrine disorders involved in the pathogenesis of refractory acne in women.
    
    Ianoşi S¹, Ianoşi G², Neagoe D³, Ionescu O⁴, Zlatian O⁵, Docea AO⁶, Badiu C⁷, Sifaki M⁸, Tsoukalas D⁸, Tsatsakis AM⁸, Spandidos DA⁹, Călina D⁴.
    
    Molecular Medicine Reports [04 Nov 2016, 14(6):5501-5506]. doi: 10.3892/mmr.2016.5924. Epub 2016 Nov 4.

24. Telomerase activity in pregnancy complications (Review). Fragkiadaki P¹, Tsoukalas D¹, Fragkiadoulaki I, Psycharakis C, Nikitovic D, Spandidos DA^, Tsatsakis AM. Mol Med Rep. 2016 Jul;14(1):16-21. doi: 10.3892/mmr.2016.5231. Epub 2016 May 9.

25. HPV strain distribution in patients with genital warts in a female population sample. Boda D¹, Neagu M², Constantin C³, Voinescu RN⁴, Caruntu C⁵, Zurac S⁶, Spandidos DA⁷, Drakoulis N⁸, Tsoukalas D⁹, Tsatsakis AM⁹. Oncol Lett. 2016 Sep;12(3):1779-1782. Epub 2016 Jul 22.
     
26. Development of a semi-automated database for telomere length statistics. Athanasios Alegkakis¹, Elena Vakonaki¹, Persefoni Fragkiadaki¹, Manolis Tzatzaraki¹, Dimitrios Tsoukalas², Aristidis Tsatsakis¹.¹Laboratory of Toxicology, University of Crete, Heraklion, Greece. ²Metabolomic Clinic, Athens, Greece. Toxicology Letters. Volume 280, Supplement 1, 20 October 2017, Page S290. https://doi.org/10.1016/j.toxlet.2017.07.670.

27. The effect of TA-65 on telomerase activation and on apoptosis in human fibroblast cells. Persefoni Fragkiadaki¹, Dimitrios Tsoukalas, Chara Vlata, Aristidis M. Tsatsakis. September 2016 Toxicology Letters. 258: S196 DOI 10.1016/j.toxlet.2016.06.1717 

28. Telomere length in opiates and cannabis abusers as a marker of early aging. Elena Vakonaki, Presefoni Fragkiadaki, Dimitrios Tsoukalas, Athanasios Alegkakis, Georgia Vaki, Konstantina Tsiminikaki, Stavros Plaitis, Manolis Tzatzarakis, Aristidis Tsatsakis. Department of Toxicology, Medical School, University of Crete, Heraklion, Greece. Toxicology Letters Volume 280, Supplement 1, 20 October 2017, Page S242. https://doi.org/10.1016/j.toxlet.2017.07.670 

29. Development of a semi-automated worksheet for predicting biological age and telomere length statistics for the Greek population. Tsoukalas D, Alegakis AK, Vakonaki E, Fragkiadaki P, Tsiminikaki K, Plaitis S, Flamourakis M, Theodorakis N, Tzatzarakis M, Tsatsakis AM. conference-abstract. International conference «Hygiene, toxicology, professional pathology: traditions and modernity», dedicated to 125 anniversary of the Federal Scientific Centre of Hygiene named after F.F.Erisman. November 9-10, 2016, Moscow.

30. The effect of supplements on telomerase activation in human PBMC cells. Toxicology Letters. ersefoni Fragkiadaki and Dimitrios Tsoukalas and Athanasios Alegakis and Chara Vlata and Christos Psycharakis and Aristeides Tsatsakis. Toxicology LettersVolume 280, Supplement 1, 20 October 2017, Page S319. https://doi.org/10.1016/j.toxlet.2017.08.063 

31. The luck of telomeres with or without the use of vitamin supplements. Vakonaki E. Fragkiadaki P, Tsoukalas D, Alegkakis A, Salatai A, Kouvidi E, Kaloudis K,  Tzatzarakis M, Tsatsakis AM. Eurotox 31 May 2016  

32. Can dietary Omega 3 fatty acids reduce asthma symptoms in children? Preliminary results of a randomized controlled trial. Maria Michelle Papamichael, Charis Katsardis, Dimitris Tsoukalas, Bircan Erbas and Catherine Itsiopoulos LaTrobe University, Australia National & Kapodistrian University of Athens, Greece European Institute of Nutritional Medicine, Italy. Pediatric Healthcare & Pediatric Infections. 10th American Pediatrics healthcare & Pediatric Infectious Diseases Congress September 20-22, 2017 | Toronto, Canada.

33. Telomeres length as ageing biomarker in glyphosate users. Tsoukalas D, Vakonaki E, Fragkiadaki P, Alegkakis A, Plaitis S, Tsiminikaki K, Vaki G, Fragkiadoulaki E, Tzatzarakis M, Tsatsakis A. BIOTECH Congress, Moscow, 20-22 February, 2017.

34. A Mediterranean diet enriched with ù3-polyunsaturated fatty acids in the management of paediatric asthma: a randomized control trial. M M Papamichael1, Ch Katsardis2, D Tsoukalas3, B Erbas1 and C Itsiopoulos1. 1La Trobe University, Australia 2National & Kapodistrian University of Athens, Greece, 3European Institute of Nutritional Medicine, Italy. 13th International Congress on Advances in Natural Medicines Nutraceuticals & Neurocognition & 14th International Conference on Clinical Nutrition, July 27-29, 2017 Rome, Italy.

35. Telomere analysis of metaphase spreads by Q-FISH in individuals of different age groups. Vakonaki E, Fragkiadaki P, Tsoukalas D, Kouvidi E, Tzatzarakis M, Alegkakis A, Vynias D, Tsatsakis AM. 9th Congress of the Turkish Society of Toxicology with the participation of the Hellenic Society of Toxicolog, October 21-24, 2015, Cesme Altin Yunus hotel, Izmir, Turkey.

36. Telomere analysis of metaphase spreads by Q-FISH in individuals of different age groups. Elena Vakonaki, Persefoni Fragkiadaki, Dimitrios Tsoukalas, Elisavet Kouvidi, Manolis Tzatzarakis, Athanasios Alegkakis,Dionisios Vynias, Aristidis M. Tsatsakis. Occupational and Environmental Diseases Congress March 2015 

37. Morbidity analysis of the National health system ambulatories in the region of Zakynthos Greece. Tsucalas D, Glezos V. 16th National Congress of General Medicine Apr 2004. 

38. Treatment of abdominal trauma in the periphery. Kosmadakis N, Tsucalas D, Kapsabellis P. 6th Peloponesian Medical Congress Oct. 2004.

39. Varicose veins - surgical treatment. Lagodimos S, Milonas I, Tsucalas D. 12th Seminar of the medical association of Corfu. Apr. 2003

40. Surgical treatment of gastric ulcer. Kapsabelis P, Palli E, Tsucalas D, 23rd National Congress of Gastroenterology Oct. 2003. 

41. Cost evaluation of pharmaceutical treatments during the year 2000 in the Urban Type National Health Center of Byron. Tsucalas D, Androulakis G. 13rd National Congress of General Medicine Apr. 2001 

42. Psychiatric disorders follow up in the Urban Type National Health Center of Byron. Tsucalas D, Papageorgaki P. 13rd National Congress of General Medicine Apr. 2001 

43. Low intraabdominal pressure during laparoscopic cholecystectomy. Bithoulkas K, Tsucalas D, Kapsabelis P. Laparoscopy 1999; 1 sup:32

44. Treatment and follow up of patients with gastro-duodenal ulcer. Svoronou A, Tsucalas D, Mylonaki D, Romanos A. 11th National congress of General Medicine. Apr. 1999 Corfu Greece.

45. Treatment and follow up of patients with intestinal polyps. Tsucalas D, Mylonaki D, Romanos A. 11th National congress of General Medicine. Apr. 1999 Corfu Greece. 

46. Comparison of different ways of chemoprofilaxis in hernial surgery. Milonaki D, Tsucalas D, Androulakis G. 3rd Symposium on the control of surgical infection Apr. 1999 Florence Italy.

47. Primary health care contribution in surgical emergency medicine. Tsucalas D, Svoronou A, Androulakis G. 10th national congress of General Medicine Apr 1998.

48. Treatment of low gastric system hemorrhage . Katergiannakis B, Tsucalas D, Androulakis G. XXI National congress of Surgery 1998 Athens Greece. 

49. Our 10 year experience on the operation of the short-period hospitalization unit. Katergiannakis B, Tsucalas D, Androukalis G. XXI National congress of Surgery 1998 Athens Greece. 

50. Addressing of patients under anticoagulant treatment in the short-period hospitalization unit. Katergiannakis B, Tsucalas D, Androukalis G. 9th Cretan congress of Surgery Nov. 1998 Herakleion Greece.

51. Addressing of patients with diabetes mellitus in the short-period hospitalization unit. Katergiannakis B, Tsucalas D, Androukalis G. 9th Cretan congress of Surgery Nov. 1998 Herakleion Greece.

52. The correction of inguinal hernia in the elderly with revised Liechtenstein technique. Kapsabelis P, Tsucalas D. 5th National congress of geriatric medicine Athens Greece. Dec 1997 

53. Acute cholecystitis, which is the timing of the surgical treatment. Kapsabellis P, Tsucalas D. British Journal of Surgery 1996. 88 sup: 9-10

54. Monografia, sindrome di Cushing, MD Thesis 1991. Tsucalas D, Prof. D'Alessandro B.
     

Scientific Activity and collaborations

• In present time collaborating with Prof. Academician A. Tsatsakis from the University of Crete Medical School Toxicology Greece, on Metabolomics and Telomere Biology. 

• Ongoing clinical trial with researcher from La Trobe University Melbourne Australia, Papamichail MM, PhD, on Mediterranean diet effect on children with asthma. 
   
• Reviewer of the Elsevier Journal Food and Chemical Toxicology.
   
• Member of the Scientific Committee of the 20th International Congress of Rural Medicine, Oct 10-12 2018. Tokyo - Japan.   
   
• Member of the Scientific Committee of the 35th Balkan Medical Week, "Healthy Ageing: an endless challenge". Athens - Greeece, Sept 25-27, 2018.  

• Collaborationg with the Department of Molecular and Translational Medicine, University of Brescia Italy, on research regarding antioxidant nutraceuticals effects on nerve cells.  

• Lecturer of Nutritional and Metabolomic Medicine at the University of Crete Medical School, 2015.

• Lecturer at the Greek Open University on Current aspects of Nutritional Medicine and Metabolomics, 2015, 2016. 

• Scientific counseling for Pharmacyclics research (California, USA) and Sierra Sciences (Nevada, USA) regarding the development of a new telomere biology therapeutic agent for degenerative diseases, 2014.

• Lecturer at the national convention for specialists in Pediatrics regarding “the new role of vitamin D in clinical practice” by invitation of the World association of Pediatrics President Prof. Andrea Konstantopoulos, 2015 and 2017.

• Publication of the book "How to live 150 years in Health". Editor Metaixmio February 2014. 

• President of the organizational committee of the 2nd European Convention of Nutritional Medicine.  Athens Greece Dec. 2013

• Member The New York Academy of Sciences. 2012

• Delegated as the President of the European Institute of Nutritional Medicine 2012. 

• President of the scientific committee of the European Convention of Metabolomic Medicine  Milan October 2012. 

• Inducted as a member of the Scientific Advisory Board of the Farsight Bioscience Ltd, society, a company of biotechnological research for metabolic diseases, listed in the Frankfurt stock market, awarded “company of the year” for 2011 in Europe, 2011

• Designated President of the European Institute of Metabolomic Medicine. 2010

• Since 2010 has been a lecturer for the postgraduate course of "Master Practitioner in eating disorders" of the British National Centre of Eating Disorders, and in Athens,Greece. 

• Inducted as a member of the International Association of Detoxification Specialists. 2006

• Lecturer of a series of courses in “Emergency Medicine” at Zakynthos General Hospital (Greece): "Mass disasters". 13/5/2004 - 2/6/2004. 

• Ålected as a member of the review committee of the Board of physicians of Zakynthos (Greece). 2004 

• Member of the European Society for Primary Care Gastroenterology. 2004

• Lecturer for post degree courses of General Medicine Ippokrateio University hospital in Athens – Greece for the 1999-2000 academic year.  Subject “Acute abdomen”, “Anemias”

• Lecturer for post degree courses of General Medicine Ippokrateio University hospital in Athens – Greece for the 1998-1999 academic year.  Subject “Differential diagnosis of chest pain” 

• Member of the organizational committee for an international symposium in Zakynthos: "Advances in Medicine and Surgery."